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Will biomarkers make cancer drug discovery cheaper and faster?
Will biomarkers make cancer drug discovery cheaper and faster? Ana Sofia Martins Increased knowledge of cancer at the cellular and molecular levels has grown exponentially in the past two decades, leading to a significant
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Liver Auto-Transplant a Complex Procedure to Treat Liver Cancer Not Otherwise Resectable
Liver Auto-Transplant a Complex Procedure to Treat Liver Cancer Not Otherwise Resectable, Cataldo Doria, MD, PhD, FACS Liver Auto-transplant is a procedure first described in the late ’80 by a German surgeon, Rudolf Pichlmayer
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Rebiopsies at time of progression could be crucial for development of new targeted therapies in EGFR TKI-resistant NSCLC
Rebiopsies at time of progression could be crucial for development of new targeted therapies in EGFR TKI-resistant NSCLC, Rafael Rosell and Niki Karachaliou. Today, thanks to considerable improvements in the characterization of human tumours, significant
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W4CS.com Cancer Support Radio – Press Release
W4CS.com Cancer Support Radio: The first cancer-dedicated radio network for patients, survivors, caregivers and families. The Intertainment Network, owner of the successful W4CY and W4WN networks, has partnered with author, caregiver, co-survivor, and show
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Sorafenib in Hepatocellular Carcinoma
Tumor response assessment to sorafenib in patients with advanced hepatocellular carcinoma: do we need new criteria? By Dr Mohmed Bouattour Sorafenib, an oral multi-tyrosine kinase inhibitor, is the first and so far the only
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A New Member of a Patient’s Healthcare Team: The Caregiver
A New Member of a Patient’s Healthcare Team: The Caregiver by Joni Aldrich Historically the patient-physician relationship has been one-on-one with less attention on others involved in the patient’s care. With the increase in
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A New Therapeutic Target to Fight Liver Cancer Discovered
A New Therapeutic Target to Fight Liver Cancer Discovered by Dr María Luz Martínez Chantar and Her Team, by Iñaki Gorostidi, responsible for press releases for CIC bioGUNE . This article is also published
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Non Small Cell Lung Cancer Treatment
Targeting c-MET in Lung Cancer. Edgardo S. Santos, M.D., FACP The role of Met in cancer was first noted in 1984 when it was cloned as a fusion oncogene from a human osteosarcoma cell
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Phenotyping Challenges in Genetically Engineered Mice
Phenotyping Challenges in Genetically Engineered Mice. Tamas Nagy1 and Sasmita Mishra 2, 1Comparative Pathology Laboratory and 2Department of Pathology, University of Georgia, Athens, GA USA. Genetically engineered mice (GEM) have enjoyed tremendous success in
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AYUDACANCER.COM obtains the certification ‘Accredited Health Web Site’
AYUDACANCER.COM obtains the certification ‘Accredited Health Web Site’ Valencia, January 24th, 2012 – AYUDACANCER.COM was certified as Accredited Health Web Site (WMA in its Spanish acronym) by the Official Medical Board of Barcelona. This
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Current Trends in Cancer Therapeutic Development
Current Trends in Cancer Therapeutic Development, Andrew Norris PhD First published on Seeking Alpha on the 24th January 2012 Friday, December 23, 2011 marked the 40th anniversary of President Richard Nixon’s declaration of a
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Improving Colorectal Cancer Screening: a Public Health Perspective Alain Braillon MD, PhD
Improving Colorectal Cancer Screening: a Public Health Perspective A systematic review and a conference statement of the National Institute of Health pointed out the need for enhancing use and quality of colorectal cancer (CRC)
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The Institute of Oncological and Molecular Medicine of Asturias (IMOMA), Dr. Santiago Vilar González
The Institute of Oncological and Molecular Medicine of Asturias (IMOMA) The IMOMA was established in spring 2008 as a private initiative of Corporation Masaveu (66%) and Cajastur (33%) to fight cancer. Our motivation is
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Melanoma: New Opportunities and New Challenges Lorenzo Alonso, MD.
Melanoma: New Opportunities and New Challenges Disseminated melanoma has traditionally been treated with a DTIC scheme given that it is the only drug showing a modest but not complete response to treatment (1). Sometimes
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The World Cancer Day: Time to Declare a Revolutionary War on all Fronts Abdul-Rahman Jazieh, MD, MPH
The World Cancer Day: Time to Declare a Revolutionary War on all Fronts. This article was first published on ASCO Connectionon the 14th January 2012 As much as we loathe wars, we should realize
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Liver Transplantation for Hepatocellular Carcinoma: Where Do We Draw the Line? Vinay Kumaran, MBBS, MS, M Ch
Hepatocellular carcinoma (HCC) is a common cancer. It usually arises in cirrhotic livers and is often detected too late for cure. Liver resection is the treatment of choice in those rare cases in which
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Interventional Radiology in the Management of Hepatocellular Carcinoma in Liver Cirrhosis: An Update. Avinash Kambadakone, M.D, F.R.C.R, Peter Mueller, M.D.
This report is an update on our previous review article published in Annals of Gastroenterology and Hepatology in 2010 in which we discussed the role of an interventional radiologist in the management of hepatocellular
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Surveillance for endometrial cancer in tam user patients Dr Mario A. Congiu, MD PhD, Dr Domenica Mazza, MD
Tamoxifen increases the risk of endometrial cancer. This and other adverse effects are balanced by an improved survival with lower incidence of contralateral breast cancer. In long term users prognosis of endometrial cancers is
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Novel therapies “targeting the heart” of osteosarcoma: 2011 review of literature
One of the most interesting areas of research in musculoskeletal oncology is treatment approaches to osteosarcoma (OS). OS is the most common primary malignant neoplasm in children and adolescents. Immunotherapy is considered a novel
Read More »The Culture of Cure—Part 2: What Is “Cure”? Abdul-Rahman Jazieh, MD, MPH
This article is based on a post first made on ASCO Connections In my first blog post on this topic, I discussed the challenges of creating a culture of cure. It seems that the
Read More »The Culture of Cure in Cancer Care, Abdul-Rahman Jazieh, MD, MPH
This blog article is based on a post first published on ASCO Connections on the 25th October 2011. I always wonder whether we have our goals of care prioritized properly when we are caring
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Field Sequential Cancerization by Miguel Bronchud
This post is based on Chapter 2 – The Multistep Field Cancerization Theory of Carcinogenesis, pp. 15-25 by Sabrina L. Spencer and Miguel H. Bronchud; in : Field Cancerization: Basic Science and Clinical Applications;
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The Yin and Yang of Cancer Therapeutics by Miguel Bronchud MA BM BCh MRCP DM PhD
To be presented at BIT’s 9th Annual Congress of International Drug Discovery Science and Technology (IDDST), November 3-6, 2011, Shenzhen, China. In 2002 I questioned the standard main current theory of carcinogenesis where a
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What’s new in breast cancer from 2011 ESMO Congress and published literature
The recent 2011 ESMO congress placed in September in Stockholm was the headquarters of a large number of presentations with interesting results in the field of advanced breast cancer. In a recent issue of
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Advances in Chemotherapy for Pure and Mixed Anaplastic Oligodendroglial Tumors: An Update
In April 2011, we published a review article on “Advances in Chemotherapy for Pure and Mixed Anaplastic Oligodendroglial Tumors” in the European Journal of Clinical and Medical Oncology, highlighting the most relevant approaches to
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Right ventricle and Iron Overload R.P Weerackody and M.A Westwood
In patients with transfusion dependent anaemias cardiac iron overload is the main cause of morbidity and mortality. Iron overload cardiomyopathy is characterised by a restrictive cardiomyopathy with prominent early diastolic dysfunction which invariably progresses
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METASTATIC CUTANEOUS MUCINOUS CARCINOMA: AN UPDATE
This report is a clinical update on our previous case report published in EJCMO in April 2011, were we presented a metastatic case with a good response to chemotherapy, specifically ciplatinum and 5 fluorouracil,
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Exploring novel therapeutic strategies for cetuximab in head and neck squamous cell carcinoma.
In April 2011 (EJCMO 2011; 3, 25-31), we published the most relevant data at that time regarding the use of epidermal growth factor receptor (EGFR) inhibitors in head and neck squamous cell carcinoma (HNSCC).
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Podcasts: ESMO 2011: Current Opinion and the Latest Oncology Research from Renowned Experts Interviewed by EJCMO.tv
Today EJCMO.tv, the on-line TV channel for the European Journal of Clinical and Medical Oncology launches a podcast interview series from ECCO-ESMO 2011, Stockholm in which some of the most eminent and world-renowned researchers
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The Positive Relationship Between Hepatic Stellate Cells and Cholangiocarcinoma
This post is a follow-up to the article entitled “The Role of Hepatic Stellate Cells in the Pathogenesis of Hepatocellular and Cholangiocarcinoma” first publsihed in the European Journal of Clinical and Medical Oncology (EJCMO)
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Chronic Lymphocytic Leukemia (CLL): Expert Debate on Current and Future Therapy
Experts (Dr Micheal Hallek, Prof Peter Hillman, Prof Wolfgang Knauf, Dr Florence Cymbalista and Dr Remi Letstu) discuss the latest clincial trial data, current and potential future standards of care, unmet needs and emerging
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Adjuvant endocrine therapy for breast cancer: sometimes less is better!
Adjuvant therapy with the selective estrogen receptor modulator tamoxifen for 5 years has produced high benefits in the treatment of women with receptor-positive breast cancer, with about 30% reductions in recurrence, contralateral disease and
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How in the world will I tell my kids? by Sue Glader
For a parent or very involved grandparent, a cancer diagnosis carries the extra emotional burden of explaining the unexplainable to your children. While this is hardly a topic covered in parenting classes, the conversation
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Quality Assurance Through Outcome Registration in Colorectal Cancer: The EURECCA Initiative.
This blog is a follow up to the original article first published in the EJCMO June 2011. Despite the numerous national audit projects, international initiatives are limited. To generate the best care for colorectal
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AML with Normal Karyotype; the Good, Bad and Ugly. Venkat Radhakrishnan MD.
Cytogenetics is the most important prognostic factor for survival in acute myeloid leukemia (AML). Adult AML is classified in to three main karyotype (cytogenetic) risk groups: favorable, intermediate, and adverse risk respectively [1]. The
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Treatment of Locally Advanced Non-Small Cell Lung Carcinoma (NSCLC): Can We Change? Michel van den Heuvel, Chest Physician, NKI-AVL.
While all oncologists dealing with advanced-stage solid malignancies are facing the reality of personalized treatment, tailored to the molecular characteristics of the tumor, the current daily reality on early stage and locally advanced stage
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The recent changes and additions to the EJCMO editorial board, discussed by Ronil Ayson, BSc, MD, Head of Publications/Editorial Director, San Lucas Medical
The European Journal of Clinical and Medical Oncology (EJCMO) has gone from strength to strength within the past 24 months, considering that the journal had a very low key launch and was originally a
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Characterization of the Differential Efficacy of Somatostatin Receptor Agonists in the Inhibition of the Growth of Experimental Gliomas and Identification of the Intracellular Mechanisms Involved by Federica Barbieri and Tullio Florio.
This is an update on the original review article entitled “Characterization of the Differential Efficiacy of Somatostatin Receptor Agonists in the Inhibition of the Growth of Experimental Gliomas and Identification of the Intracellular Mechanisms
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Physician Dispensing- A Growing Trend Between Medical Practices
Physician dispensing is the process of distributing pre-packaged medications directly to your patients at the point of care. Many providers are adding physician drug dispensing to their practices as a way to heighten the
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Oncosurgical Approach in Unresectable Stage IV Colorectal Cancer: An Update by Drs Andrés J. Muñoz Martín & Rebeca Mondéjar Solís
The original article “Oncosurgical Approach in Unresectable Stage IV Colorectal Cancer” was first published in the EJCMO in June 2011. Andrés J. Muñoz Martín MD, Rebeca Mondéjar Solís MD. GI Section. Medical Oncology Service,
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Automating the Diagnostic Process by Yaser Alyounes, Toronto, Ontario, Canada
As the use of technology in health care plays a bigger role in various aspects of health care nowadays, ranging from patient scheduling to statistical analysis of medical documentation, one cannot help but wonder
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What is Bioentrepreneurship Anyway? Arlen D Meyers, MD, MBA Denver, Colorado
Does this sound familiar? In the operating room, you use an instrument that is unwieldy or doesn’t completely get the job done. At the bedside, you waste a lot of time changing dressings or
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Cardiac MRI T2* Calibration is Here
An update on the recently published article – Current Strategies in the Assessment of Iron Overload in the EJCMO by Ali T. Taher1, Khaled M. Musallam1, A.V. Hoffbrand2 1Department of Internal Medicine, Division of
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Collaboration and the power of the health care community through web 2.0 and social media
The first international event dedicated to social media and health care took place on June 22nd & 23rd in Paris. Doctors 2.0, organised by Basil Strategies in collaboration with an advisory board of health
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Navigating the Insurance Claims Payment Super-Highway
By Aaron Jones, ICP, IFI, MM, MRM I have seen many comments and professional literature saying that you have to play the insurance game, or how insurance pays is a mystery. In one publication
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Targeting Angiogenesis in Esophagogastric Adenocarcinoma – An update for Clinicians & Researchers
An interview with Dr Alicia Okines & Prof David Cunningham (The Royal Marsden Hospital, London and Surrey, United Kingdom), discussing their review article which was recently accepted for publication in The Oncologist. Q. What
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Extreme scenarios for European healthcare
Rising costs, aging population and a host of other factors are causing us to radically rethink the future and better prepare for it. Chronic conditions such as cancer take up to 75% of healthcare
Read More »EJCMO.tv launched with interviews on CLL from EHA 2011
Ejcmo.tv is editorially independent of any commercial interests and is led by an editorial board of world renowned oncologists
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Prof. Wolfgang Knauf: Updates in Chronic Lymphocytic Leukemia
An interview with Professor Wolfgang Knauf: Updates in Chronic Lymphocytic Leukemia
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